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Reviews of the disease support the broad picture, describing MASH as a metabolically driven process in which excess fatty acids and toxic lipid intermediates can promote hepatocyte stress, macrophage activation and fibrotic signaling

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A More recently, a 2024 study suggests that boosting levels of glutathione might help prevent or manage type 2 diabetes

Human tolerability data comes from Phase I and II clinical investigations in obese adult volunteers

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